Jen Crainic, BS

I joined the PIGI lab as a research tech in January 2020 after graduating from Oberlin College in December with a BA in Biology. I have a broad interest in conditioning the tumor microenvironment to generate targetable dependencies that may be exploited when developing cancer therapeutics. Trans-arterial chemoembolization (TACE) is a locoregional therapy that combines embolization of the hepatic artery with intra-arterial chemotherapy and is the most common procedure to treat liver cancer patients that are not eligible for a transplant. My project in the PIGI lab is centered on designing a more potent TACE cocktail based on targeting the metabolic stress response. I work specifically with LDH, UPR and autophagy inhibitors. Outside of lab, I enjoy teaching fitness classes, biking, and snuggling with my guinea pigs!